Fleet Glycerin Rectal Suppository: Uses, Side Effects, Dosages, & More

Cameron-Leigh Henning
By Cameron-Leigh Henning
Joel Taylor
Edited by Joel Taylor

Published December 31, 2021.

Our team independently researches and recommends the best products for women's health. We publish unbiased reviews and are not influenced by payments we may receive from advertising partners.

A promotional image for Fleet Glycerin Suppositories

Fleet glycerin suppositories are used as a laxative and relieve occasional constipation or cleanse the intestines and bowel before a rectal exam or surgery.

A promotional image for Fleet Glycerin Suppositories


  • Quick results
  • Great alternative for people who can't swallow pills
  • Safe for all ages
  • No known interactions with pharmaceutical drugs


  • May be uncomfortable to insert the suppository
  • Prolonged use can result in a laxative dependence

How Do Fleet Glycerin Suppositories Work?

Fleet glycerin liquid suppositories belong to a class of drugs known as hyperosmotic laxatives and work by drawing more water into the intestines, resulting in a bowel movement.

How Quickly Do Fleet Glycerin Suppositories Take to Work?

They usually cause a bowel movement within 15 to 20 minutes.

Who Are Fleet Glycerin Suppositories Best For?

This product is for rectal use only. Fleet glycerin laxative suppositories can be used by those who need quick relief from temporary constipation and are not meant to treat chronic constipation unless recommended by a health care practitioner.

Fleet Suppository Instructions

Be sure to read and follow all the directions on the product label or use as directed by your health practitioner. If the suppository is too soft to insert, run cold water over it before removing the wrapper or chill it in the refrigerator for half an hour.

How to Insert a Glycerin Suppository

Wash your hands and unwrap the medication. Do not use petroleum jelly or mineral oil, which might cause the suppository to be less effective.

  1. Lie on your left side with your right knee slightly bent.
  2. Use your fingers to gently insert the medication, pointed end first, well up into your rectum.
  3. After you’ve inserted the suppository, stay in that position for 15 to 20 minutes until you feel an urge to use the bathroom.
  4. The suppository does not need to dissolve completely for it to begin working.

Are Fleet Glycerin Suppositories Safe to Use?

The suppository is safe to use within the intended dosage. If used too often, it may result in a loss of normal bowel function. Follow the instructions on the label or from your doctor.


  • Adults One 2-2.8 g suppository
  • Children over 6 years One 2-8 g suppository
  • Children 2-6 years One 1-1.7 g suppository

How Often Can You Use Fleet Glycerin Suppositories?

The suppository should be used as needed for constipation and should not be used more than once a day unless specifically directed by your doctor. Long-term use can result in laxative dependence.

Dangers of Swallowing a Suppository

This medication may be harmful if swallowed, and you should consult your doctor if this occurs. The effects of swallowing a glycerin suppository could result in:

  • Stomach pain
  • Vomiting
  • Nausea
  • Diarrhea
  • Headaches
  • Tremors
  • Lethargy


Consult your doctor about your medical history before using glycerin suppositories, especially if you’ve had rectal bleeding, hemorrhoids, abdominal pain, vomiting, nausea, intestinal blockages, or ulcerative colitis. Check with your doctor if you’ve had a change in bowel movements lasting more than two weeks. Precaution should be taken with pregnant and breastfeeding women, and this medication should only be used when needed with a doctor’s permission.

Side Effects of Using Fleet Glycerin Suppositories

If any side effects persist or worsen, it is advised to stop the medication and consult your doctor.

Common Side Effects

  • Abdominal discomfort
  • Cramping
  • Rectal irritation or burning
  • Small amounts of mucus in the stool

Severe Side Effects

  • Severe and persistent abdominal pain
  • Bloody stool
  • Rectal bleeding
  • Persistent diarrhea
  • Persistent urge to have a bowel movement


Before using Fleet suppositories, consult with your doctor and ensure you’re not allergic to any of the ingredients. Symptoms of an allergy may include reactions like:

  • Rashes
  • Hives
  • Itching
  • Swollen, red, blistered, or peeling skin
  • Fever
  • Wheezing
  • Tightness in throat or chest
  • Difficulty breathing, swallowing, or talking
  • Swelling of the face, mouth, lips, tongue, or throat


  • Severe stomach pain
  • Rectal bleeding


There are no known interactions with other drugs.

Fleet Glycerin Suppositories Pricing

The cost for Fleet is around $11 for a supply of 12 suppositories.

Why You Should Use Fleet Glycerin Suppositories

Fleet Glycerin Suppositories are very beneficial in providing quick relief from occasional constipation when you don’t want to wait hours for the medication to work.

Fleet Glycerin Rectal Suppository: Uses, Side Effects, Dosages, & More

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