What Is the ERA Test in IVF?

Find out what the ERA test is, what role it plays in IVF treatment, whether it is worth it, and when it is deemed necessary for you to undergo the procedure.

By Caroline Ikiugu
Edited by Taj Schlebusch

Published October 30, 2021.

In Vitro Fertilization (IVF) is a medical procedure where mature eggs are removed from a woman’s ovary and fertilized by sperm outside the body. The fertilization can happen by mixing the ovum with sperm in a petri dish or injecting the sperm directly into the egg. The fertilized egg (zygote) is then transferred to the uterus for implantation.

If you’ve had two or more unsuccessful transfers in IVF where the zygote fails to implant despite being of good quality, you may consider the Endometrial Receptivity Analysis/ Array (ERA) test.

The ERA test provides insight into the health of the endometrium and helps determine the best window for zygote implantation. ERA helps your fertility doctor to uncover and evaluate issues with the endometrium lining of the uterus that may lead to failed implantation.

How Is an ERA Test Performed?

The procedure is done by inserting a thin catheter through the cervix into the uterus. Once in position, a plunger in the catheter is used to create suction, withdrawing a small sample of endometrial tissue. This sample is then sent to the lab for analysis.

The procedure takes about 10-15 minutes, and the results are available in about 3 weeks and cost $700-$1550 depending on the clinic you go to.

The ERA test may be uncomfortable and even painful, but this is often over quickly. You may also experience some slight spotting or cramping afterward.

Does an ERA Test Increase the Chances of Pregnancy?

The ERA test provides valuable information on the health of the endometrium and can help determine the best time for implanting an embryo during the IVF cycle. This increases the chances of implantation and pregnancy.

Is an ERA Test Necessary for IVF?

While ERA is not necessary for IVF, it is recommended for women who have had several unsuccessful embryo transfers. It can increase the chances of successful zygote implantation and, therefore, pregnancy.